Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21650358 | 0.90 | ALDH1A1 (0.57) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL18580814 | 0.88 | ALDH1A1 (0.57) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL21471161 | 0.84 | HTT (0.58) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL18579907 | 0.83 | HTT (0.51) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL10677656 | 0.81 | HTT (0.61) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL18612170 | 0.81 | HTT (0.66) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL17859587 | 0.81 | HTT (0.66) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL10963796 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL21043548 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 | |
| SCHEMBL18612203 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP1A2HPGDNPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11083717-B2 | Compositions and methods for drug sensitization of parasites | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200138796-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138796-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | ABCC1, SLC11A2, ABCG2 | ALDH1A1 839/4885CYP1A2 90/4885HPGD 313/4885 |
| US-11083717-B2 | Compositions and methods for drug sensitization of parasites | ABCC1, SLC11A2, ABCG2 | ALDH1A1 839/4885CYP1A2 90/4885HPGD 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.