Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509575 | 0.81 | FFAR1 (0.48) | FFAR1CTSA | |
| SCHEMBL22627151 | 0.81 | FFAR1 (0.42) | MEN1KMT2AFFAR1CYP4F2CYP4A11 | |
| SCHEMBL3015067 | 0.81 | MEN1 (0.56) | MEN1KMT2APPARGPPARA | |
| SCHEMBL31391955 | 0.81 | FFAR1 (0.44) | MEN1KMT2AFFAR1CYP4F2CYP4A11 | |
| SCHEMBL1233549 | 0.81 | MEN1 (0.66) | MEN1KMT2ATAAR1CHRM2CHRM1 | |
| SCHEMBL4850094 | 0.81 | TSHR (0.49) | MEN1KMT2AFFAR1CYP4F2CYP4A11 | |
| SCHEMBL14122832 | 0.81 | FFAR1 (0.44) | MEN1KMT2AFFAR1CYP4F2CYP4A11 | |
| SCHEMBL4487429 | 0.81 | KDM4E (0.49) | FFAR1 | |
| SCHEMBL4849887 | 0.81 | FFAR1 (0.44) | MEN1KMT2AFFAR1CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL25369506 | 0.79 | MAOB (0.46) | FFAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343298-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2020-05-06 | — | — | EP | disclosed |