Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12551564 | 0.81 | LMNA (0.46) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL21845649 | 0.81 | CYP3A4 (0.57) | CYP3A4TDP1KDM4EESR1ESR2 | |
| Triphenylphosphine Oxide SCHEMBL5091574 | 0.79 | TDP1 (0.60) | CYP3A4TDP1LMNAKMT2AMEN1 | |
| SCHEMBL22180734 | 0.78 | TDP1 (0.48) | CYP3A4TDP1LMNAKMT2AMEN1 | |
| SCHEMBL19678155 | 0.78 | CYP3A4 (0.40) | CYP3A4TDP1LMNAKMT2AMEN1 | |
| Triphenylphosphine Oxide SCHEMBL27470482 | 0.77 | TDP1 (0.57) | CYP3A4TDP1LMNAKMT2AMEN1 | |
| SCHEMBL28087764 | 0.75 | TDP1 (0.55) | CYP3A4TDP1LMNAKMT2AMEN1 | |
| SCHEMBL13156266 | 0.74 | KMT2A (0.37) | CYP3A4TDP1LMNAKMT2AMEN1 | |
| SCHEMBL25687646 | 0.74 | KDM4E (0.42) | CYP3A4TDP1KDM4EALDH1A1NPSR1 | |
| SCHEMBL15698178 | 0.72 | LMNA (0.44) | LMNAKMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627730-B1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |