Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PKLR | P30613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20090883 | 0.91 | ADORA2A (0.31) | — | |
| SCHEMBL18171979 | 0.89 | — | — | |
| SCHEMBL18181472 | 0.85 | NPC1 (0.35) | PKM | |
| SCHEMBL18171964 | 0.81 | — | — | |
| SCHEMBL20090940 | 0.80 | DDR1 (0.32) | PKMPKLR | |
| SCHEMBL21974664 | 0.80 | — | — | |
| SCHEMBL24369945 | 0.78 | MAOB (0.31) | — | |
| SCHEMBL22291717 | 0.78 | DDR1 (0.32) | — | |
| SCHEMBL18171956 | 0.77 | — | — | |
| SCHEMBL17494927 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |