Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21974662 | 0.91 | PKM (0.30) | — | |
| SCHEMBL18171964 | 0.90 | — | — | |
| SCHEMBL21974086 | 0.86 | ALDH1A1 (0.31) | ALDH1A1MAPK1SMN1; SMN2DDR1 | |
| SCHEMBL20086329 | 0.86 | RAD51 (0.33) | ADORA2AALDH1A1MAPK1 | |
| SCHEMBL18181314 | 0.84 | DDR1 (0.34) | DDR1 | |
| SCHEMBL21974261 | 0.84 | TRPC5 (0.34) | ADORA2AALDH1A1SMN1; SMN2DDR1 | |
| SCHEMBL20090863 | 0.82 | DDR1 (0.32) | ADORA2ASMN1; SMN2DDR1PDE7A | |
| SCHEMBL18171979 | 0.80 | — | — | |
| SCHEMBL18073404 | 0.80 | KDR (0.34) | ADORA2AALDH1A1SMN1; SMN2DDR1 | |
| SCHEMBL22291718 | 0.79 | DDR1 (0.34) | ADORA2ADDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| US-20180110226-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110226-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SQOR, DDT, QSOX1 | ADORA2A 4428/4885ALDH1A1 1226/4885MAPK1 2916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.