Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26938101 | 0.86 | HTT (0.35) | PDE2ALMNA | |
| SCHEMBL10304787 | 0.85 | PDE2A (0.52) | PDE2AALDH1A1HPGDTRPA1LMNA | |
| SCHEMBL14997534 | 0.84 | CNR1 (0.36) | PDE2AALDH1A1HPGDTRPA1LMNA | |
| SCHEMBL11443449 | 0.83 | TSHR (0.42) | ALDH1A1HPGDTRPA1LMNACHRM1 | |
| SCHEMBL26200269 | 0.82 | PDE2A (0.37) | PDE2AALDH1A1HPGDTRPA1LMNA | |
| SCHEMBL26137708 | 0.82 | PDE2A (0.53) | PDE2A | |
| SCHEMBL20826211 | 0.79 | PDE2A (0.34) | PDE2A | |
| SCHEMBL15801257 | 0.79 | TRPA1 (0.41) | PDE2AALDH1A1HPGDTRPA1LMNA | |
| SCHEMBL20811699 | 0.78 | PDE2A (0.40) | PDE2A | |
| SCHEMBL20811766 | 0.78 | PDE2A (0.36) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286186-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |