Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | PDE8B | O95263 | 4/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21975302 | 0.89 | PDE8B (0.32) | ADORA2AADORA2BTLR7PDE8BCA2 | |
| SCHEMBL12157657 | 0.86 | PDE8B (0.38) | ADORA2AADORA3ADORA1ADORA2BTLR7 | |
| SCHEMBL4554123 | 0.85 | PDE8B (0.39) | ADORA2AADORA3ADORA1ADORA2BTLR7 | |
| SCHEMBL2199473 | 0.85 | PDE8B (0.39) | ADORA2AADORA3ADORA1ADORA2BTLR7 | |
| SCHEMBL21975299 | 0.83 | TP53 (0.45) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL2199490 | 0.82 | ADORA2A (0.46) | ADORA2AADORA3ADORA1ADORA2BTLR7 | |
| SCHEMBL12726866 | 0.80 | TLR7 (0.41) | ADORA2AADORA3ADORA1ADORA2BTLR7 | |
| SCHEMBL2198592 | 0.79 | TLR7 (0.41) | ADORA2AADORA3ADORA1ADORA2BTLR7 | |
| SCHEMBL567681 | 0.78 | TLR7 (0.48) | ADORA2AADORA2BTLR7 | |
| SCHEMBL29809145 | 0.78 | TLR7 (0.48) | ADORA2AADORA2BTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355933-B1 | ADENINE CONJUGATE COMPOUNDS AND THEIR USE AS VACCINE ADJUVANTS | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |