Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567681 | 1.00 | TLR7 (0.48) | TLR7ADORA2AADORA2BTLR8 | |
| SCHEMBL2197624 | 0.89 | TLR7 (0.38) | TLR7ADORA2AADORA2B | |
| SCHEMBL24733095 | 0.89 | TLR7 (0.49) | TLR7 | |
| SCHEMBL2198592 | 0.89 | TLR7 (0.41) | TLR7ADORA2AADORA2B | |
| SCHEMBL31124752 | 0.88 | ADORA2A (0.41) | TLR7ADORA2AADORA2B | |
| SCHEMBL567233 | 0.87 | TLR7 (0.47) | TLR7ADORA2AADORA2BTLR8 | |
| SCHEMBL19050043 | 0.87 | YTHDC1 (0.44) | TLR7TLR8 | |
| SCHEMBL2195612 | 0.87 | ADORA2A (0.42) | TLR7ADORA2AADORA2B | |
| SCHEMBL29809327 | 0.87 | TLR7 (0.47) | TLR7ADORA2AADORA2BTLR8 | |
| SCHEMBL2199789 | 0.87 | ADORA2A (0.44) | TLR7ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119455004-A | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119455003-A | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113660957-B | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |