Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 19/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21975972 | 0.87 | PKLR (0.70) | PKLR | |
| SCHEMBL21976611 | 0.87 | PKLR (0.59) | PKLR | |
| SCHEMBL21976596 | 0.85 | PKLR (0.58) | PKLR | |
| SCHEMBL16049746 | 0.83 | PKLR (0.78) | PKLR | |
| SCHEMBL21976622 | 0.82 | PKLR (0.70) | PKLR | |
| SCHEMBL21976568 | 0.81 | PKLR (0.70) | PKLRAVPR1A | |
| SCHEMBL21976225 | 0.80 | PKLR (0.71) | PKLR | |
| SCHEMBL21976171 | 0.80 | PKLR (0.69) | PKLRAVPR1A | |
| SCHEMBL21976594 | 0.79 | PKLR (0.60) | PKLR | |
| SCHEMBL21976246 | 0.79 | PKLR (0.65) | PKLRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970189-B1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS INC (US) | 2020-05-06 | — | — | EP | disclosed |