Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 12/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16084080 | 0.84 | PKLR (1.00) | PKLRRXFP1ALDH1A1POLBHPGD | |
| SCHEMBL16083913 | 0.77 | PKLR (0.72) | PKLR | |
| SCHEMBL15713347 | 0.75 | PKLR (0.83) | PKLRRXFP1ALDH1A1POLBHPGD | |
| SCHEMBL16083871 | 0.74 | PKLR (0.82) | PKLRRXFP1ALDH1A1POLBCYP3A4 | |
| SCHEMBL16084069 | 0.72 | PKLR (1.00) | PKLRALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16083896 | 0.71 | PKLR (1.00) | PKLR | |
| SCHEMBL16049722 | 0.70 | PKLR (1.00) | PKLR | |
| SCHEMBL21976816 | 0.70 | PKLR (0.65) | PKLR | |
| SCHEMBL16083997 | 0.70 | PKLR (0.77) | PKLR | |
| SCHEMBL16084007 | 0.68 | PKLR (0.54) | PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970189-B1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS INC (US) | 2020-05-06 | — | — | EP | disclosed |