Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.50 |
| ▸ | NAMPT | P43490 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959745 | 0.87 | GCK (0.58) | GCK | |
| SCHEMBL1959747 | 0.87 | GCK (0.58) | GCK | |
| SCHEMBL2176106 | 0.85 | GCK (0.49) | GCKNAMPT | |
| SCHEMBL1962540 | 0.80 | GCK (0.56) | GCK | |
| SCHEMBL1963036 | 0.79 | GCK (0.56) | GCK | |
| SCHEMBL1960807 | 0.79 | GCK (0.57) | GCK | |
| SCHEMBL1961027 | 0.79 | GCK (0.57) | GCK | |
| SCHEMBL1960236 | 0.79 | GCK (0.56) | GCK | |
| SCHEMBL1961944 | 0.78 | GCK (0.55) | GCK | |
| SCHEMBL1960816 | 0.78 | GCK (0.51) | GCKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |