Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178618 | 0.85 | GCK (0.52) | GCK | |
| SCHEMBL2197922 | 0.85 | GCK (0.50) | GCKNAMPT | |
| SCHEMBL2180161 | 0.80 | NAMPT (0.37) | KDM4ENAMPT | |
| SCHEMBL1960871 | 0.74 | GCK (0.61) | GCK | |
| SCHEMBL2199152 | 0.74 | GCK (0.73) | GCK | |
| SCHEMBL1958744 | 0.73 | GCK (0.60) | GCK | |
| SCHEMBL1960910 | 0.73 | GCK (0.65) | GCK | |
| Hydrochloric Acid SCHEMBL1962614 | 0.73 | GCK (0.60) | GCK | |
| SCHEMBL1958746 | 0.73 | GCK (0.60) | GCK | |
| SCHEMBL2195760 | 0.73 | GCK (0.70) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |