⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21979389 | 0.98 | — | — | |
| SCHEMBL20551135 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL20551723 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL18335403 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL18335377 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL1129493 | 0.74 | USP2 (0.33) | — | |
| SCHEMBL302071 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL15187 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL153517 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL4874234 | 0.72 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630776-B1 | FURO[2,3-B]PYRAN-2-ONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2023-05-17 | — | — | EP | claimed |
| US-10941155-B2 | Furo[2,3-b]pyran-2-one compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-03-09 | — | — | US | claimed |
| US-20200165263-A1 | FURO[2,3-b]PYRAN-2-ONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-05-28 | — | — | US | claimed |
| EP-3630776-B1 | FURO[2,3-B]PYRAN-2-ONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2023-05-17 | — | — | EP | disclosed |
| US-10941155-B2 | Furo[2,3-b]pyran-2-one compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-03-09 | — | — | US | disclosed |
| US-10941155-B2 | Furo[2,3-b]pyran-2-one compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-03-09 | — | — | US | disclosed |
| US-20200165263-A1 | FURO[2,3-b]PYRAN-2-ONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-05-28 | — | — | US | disclosed |
| US-20200165263-A1 | FURO[2,3-b]PYRAN-2-ONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-05-28 | — | — | US | disclosed |