Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714109 | 1.00 | ATM (0.48) | ATMAOC3LTA4HKMT2AMEN1 | |
| SCHEMBL17901117 | 1.00 | ATM (0.48) | ATMAOC3LTA4HKMT2AMEN1 | |
| SCHEMBL19726546 | 0.85 | AOC3 (0.47) | ATMAOC3LTA4HKMT2AMEN1 | |
| SCHEMBL28508515 | 0.82 | ATM (0.48) | ATMAOC3LTA4HKMT2AMEN1 | |
| SCHEMBL21440869 | 0.82 | ATM (0.48) | ATMAOC3LTA4HKMT2AMEN1 | |
| SCHEMBL17896161 | 0.82 | ATM (0.48) | ATMAOC3LTA4HKMT2AMEN1 | |
| SCHEMBL3932308 | 0.79 | LTA4H (0.58) | ATMAOC3LTA4HKMT2AMEN1 | |
| SCHEMBL21980708 | 0.78 | LTA4H (0.49) | AOC3LTA4HKMT2AMEN1TDP1 | |
| SCHEMBL17901310 | 0.78 | LTA4H (0.49) | AOC3LTA4HKMT2AMEN1TDP1 | |
| SCHEMBL17892005 | 0.78 | LTA4H (0.49) | AOC3LTA4HKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |