Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23735441 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL24507862 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL22079314 | 0.65 | — | — | |
| SCHEMBL18377511 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL20968423 | 0.62 | TSHR (0.30) | — | |
| SCHEMBL23252548 | 0.62 | TSHR (0.30) | — | |
| SCHEMBL18599675 | 0.62 | TSHR (0.39) | — | |
| SCHEMBL24611354 | 0.61 | KISS1R (0.33) | KISS1R | |
| SCHEMBL20967260 | 0.61 | — | — | |
| SCHEMBL14417120 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019480-B1 | 2,4- OR 4,6-DIAMINOPYRIMIDINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER | AGIOS PHARMACEUTICALS INC (US) | 2020-05-06 | — | — | EP | disclosed |