⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881350 | 0.92 | — | — | |
| SCHEMBL14959992 | 0.89 | ALDH1A1 (0.39) | — | |
| SCHEMBL26385371 | 0.79 | — | — | |
| SCHEMBL8440343 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL27383654 | 0.74 | — | — | |
| SCHEMBL1938236 | 0.73 | — | — | |
| SCHEMBL13613378 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL27378815 | 0.72 | — | — | |
| SCHEMBL6336160 | 0.71 | — | — | |
| SCHEMBL10899490 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220298133-A1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | NXERA PHARMA UK LIMITED (GB) | 2022-09-22 | — | — | US | disclosed |
| US-20200165220-A1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | NXERA PHARMA UK LIMITED (GB) | 2020-05-28 | — | — | US | disclosed |