Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978037 | 0.87 | LMNA (0.77) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL3614366 | 0.86 | LMNA (0.75) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL5584678 | 0.86 | LMNA (0.75) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL4745478 | 0.86 | KMT2A (1.00) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL4209809 | 0.86 | LMNA (0.75) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL10651238 | 0.83 | LMNA (0.71) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL29902855 | 0.83 | LMNA (0.71) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL25062697 | 0.83 | LMNA (0.71) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL7055795 | 0.83 | LMNA (0.71) | LMNARECQLALDH1A1KMT2ARAB9A | |
| SCHEMBL14259653 | 0.83 | LMNA (0.71) | LMNARECQLALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597093-B1 | BENZOFURANONE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | FUSO PHARMACEUTICAL IND (JP) | 2014-11-05 | — | — | EP | claimed |
| US-8563743-B2 | Benzofuranone compound and pharmaceutical composition containing same | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2013-10-22 | — | — | US | claimed |
| EP-2597093-A1 | BENZOFURANONE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Fuso Pharmaceutical Industries, Ltd. (JP) | 2013-05-29 | — | — | EP | claimed |
| US-20130123313-A1 | BENZOFURANONE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2013-05-16 | — | — | US | claimed |
| CN-102997991-A | Ultraviolet detection device | LIYANG PRODUCTIVITY PROMOTION CT | 2013-03-27 | — | — | CN | claimed |
| US-20240083857-A1 | 2-Methyl-Quinazolines | Bayer Pharma AG (DE) | 2024-03-14 | — | — | US | disclosed |
| WO-2023178040-A2 | INHIBITORS OF EWS-FLI1 | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-09-21 | — | — | WO | disclosed |
| CN-116234800-A | Copper complexes for the treatment of neurodegenerative disorders | ALS治疗发展学会 | 2023-06-06 | — | — | CN | disclosed |
| CN-111808056-B | Dopamine D 2 Receptor selective agonists and their use in the treatment of disease | 中国科学院分子细胞科学卓越创新中心 | 2022-08-23 | — | — | CN | disclosed |
| US-20220235013-A1 | 2-METHYL-QUINAZOLINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-07-28 | — | — | US | disclosed |
| US-10870635-B2 | Compounds and their use as BACE1 inhibitors | ALLGENESIS BIOTHERAPEUTICS, INC. (TW) | 2020-12-22 | — | — | US | disclosed |
| CN-107613771-B | Compounds and their use as beta-secretase 1 inhibitors | 新源生物科技股份有限公司 | 2020-12-15 | — | — | CN | disclosed |
| EP-0873331-A1 | BENZOFURAN CARBOXAMIDES AND SULPHONAMIDES | Darwin Discovery Limited (GB) | 1998-10-28 | — | — | EP | disclosed |
| US-5773467-A | Benzofuran sulphonanmides | CHIROSCIENCE, LTD. (GB) | 1998-06-30 | — | — | US | disclosed |
| WO-1997044337-A1 | BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LIMITED (GB) | 1997-11-27 | — | — | WO | disclosed |
| WO-1997020833-A1 | BENZOFURAN CARBOXAMIDES AND SULPHONAMIDES | DARWIN DISCOVERY LIMITED (GB) | 1997-06-12 | — | — | WO | disclosed |
| EP-0187387-B1 | BENZOFURAN DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0187387-A1 | Benzofuran derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-07-16 | — | — | EP | disclosed |
| US-4006234-A | Substituted 2-benzofuranyl propenones as anti-tubercular agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3931157-A | ANTITUBERCULAR | AMERICAN CYANAMID COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870635-B2 | Compounds and their use as BACE1 inhibitors | BACE1, BACE2, APP | LMNA 291/4885RECQL 1321/4885ALDH1A1 2022/4885 |
| US-20240083857-A1 | 2-Methyl-Quinazolines | NRAS, KRAS, KSR2 | LMNA 3538/4885RECQL 932/4885ALDH1A1 4417/4885 |
| US-20130123313-A1 | BENZOFURANONE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDAC10, RB1 | LMNA 2140/4885RECQL 885/4885ALDH1A1 90/4885 |
| US-20220235013-A1 | 2-METHYL-QUINAZOLINES | NRAS, KRAS, KSR2 | LMNA 3538/4885RECQL 932/4885ALDH1A1 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.