Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21981397 | 1.00 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL28617007 | 0.93 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL28617005 | 0.93 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL20516080 | 0.93 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL22962329 | 0.93 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL20669327 | 0.93 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL22962260 | 0.92 | REN (0.61) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL20669112 | 0.91 | REN (0.60) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL18229263 | 0.91 | REN (0.60) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL12242945 | 0.90 | REN (0.62) | RENCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656782-B1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2021-12-22 | — | — | EP | disclosed |
| EP-3656782-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2020-05-27 | — | — | EP | disclosed |
| US-9422295-B2 | Deuterated ibrutinib | CONCERT PHARMACEUTICALS, INC. (US) | 2016-08-23 | — | — | US | disclosed |