Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2256495 | 0.90 | KDM4E (0.57) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL19945109 | 0.90 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL22383229 | 0.90 | SMN1; SMN2 (0.49) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL19039897 | 0.90 | SMN1; SMN2 (0.48) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL17598592 | 0.90 | SMN1; SMN2 (0.45) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL17598677 | 0.90 | SMN1; SMN2 (0.45) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL2951921 | 0.89 | KDM4E (0.53) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL17944674 | 0.89 | KDM4E (0.58) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL9958139 | 0.88 | ALDH1A1 (0.47) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 | |
| SCHEMBL17720967 | 0.88 | GRM5 (0.48) | KDM4ESMN1; SMN2HSD17B10TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020085319-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2020-04-30 | — | — | WO | disclosed |