⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20862244 | 0.76 | — | — | |
| SCHEMBL4108228 | 0.74 | — | — | |
| SCHEMBL21715761 | 0.72 | — | — | |
| SCHEMBL14868284 | 0.71 | — | — | |
| SCHEMBL19050598 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL1937317 | 0.69 | GRIN2D (0.32) | — | |
| SCHEMBL20000832 | 0.69 | GRIN2D (0.31) | — | |
| SCHEMBL23685203 | 0.69 | — | — | |
| SCHEMBL7772449 | 0.68 | NOS3 (0.33) | — | |
| SCHEMBL14868274 | 0.68 | SPHK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11065215-B2 | Biguanide compositions and methods of treating metabolic disorders | ANJI PHARMA (US) LLC (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200138751-A1 | Biguanide Compositions and Methods of Treating Metabolic Disorders | ANJI PHARMACEUTICALS INC. | 2020-05-07 | — | — | US | disclosed |