Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558124 | 0.84 | NPSR1 (0.47) | NPSR1HMGB1CXCL12KDM4EGAA | |
| SCHEMBL12931051 | 0.80 | NPSR1 (0.47) | NPSR1HMGB1CXCL12KDM4EGAA | |
| SCHEMBL15957874 | 0.79 | NPSR1 (0.45) | NPSR1HMGB1CXCL12KDM4EGAA | |
| SCHEMBL70135 | 0.77 | KDM4E (0.54) | HMGB1CXCL12KDM4EGAAHPGD | |
| SCHEMBL25705377 | 0.76 | MRGPRX4 (0.47) | HPGDHSD17B10ALDH1A1EPHX2NR1H4 | |
| SCHEMBL19050227 | 0.76 | EPHX2 (0.60) | KDM4EGAAHSD17B10ALDH1A1EPHX2 | |
| SCHEMBL10172953 | 0.76 | NPSR1 (0.52) | NPSR1HMGB1CXCL12KDM4EGAA | |
| SCHEMBL1251782 | 0.75 | SLC6A4 (0.43) | NPSR1KDM4EGAAHSD17B10ALDH1A1 | |
| SCHEMBL5460255 | 0.75 | EPHX2 (0.42) | HTTKDM4EGAAHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL4352648 | 0.75 | KDM4E (0.52) | HMGB1CXCL12KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448849-B1 | SYNTHESIS OF INDAZOLES | Bayer Pharma AG (DE) | 2020-05-13 | — | — | EP | disclosed |