Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12931051 | 0.87 | NPSR1 (0.47) | NPSR1HMGB1CXCL12ALDH1A1KDM4E | |
| SCHEMBL15957874 | 0.85 | NPSR1 (0.45) | NPSR1HMGB1CXCL12ALDH1A1KDM4E | |
| SCHEMBL21985448 | 0.84 | NPSR1 (0.41) | NPSR1HMGB1CXCL12ALDH1A1KDM4E | |
| SCHEMBL70135 | 0.83 | KDM4E (0.54) | HMGB1CXCL12ALDH1A1KDM4EHPGD | |
| SCHEMBL10172953 | 0.82 | NPSR1 (0.52) | NPSR1HMGB1CXCL12KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL4352648 | 0.81 | KDM4E (0.52) | HMGB1CXCL12ALDH1A1KDM4EHPGD | |
| Ethylene Glycol SCHEMBL27658105 | 0.79 | KDM4E (0.47) | HMGB1CXCL12ALDH1A1KDM4EHPGD | |
| SCHEMBL9557807 | 0.79 | KDM4E (0.50) | NPSR1HMGB1CXCL12ALDH1A1KDM4E | |
| SCHEMBL17244910 | 0.79 | GABRP (0.50) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27684889 | 0.79 | NPSR1 (0.40) | NPSR1HMGB1CXCL12ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332425-B1 | PROCESS FOR REFINING 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND A PROCESS FOR PREPARING AN AROMATIC POLYAMIDE BY USE OF THE REFINED PRODUCT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5075406-A | Solution polymerization of polyamides in solvent purified by adsorption on magnesia, alumina, silica or mixed oxides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5011936-A | Using composite salt consisting of at least two of silica, magnesia and alumina | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4923951-A | DIISOCYANTE, ALKALI OR ALKALINE EARTH METAL CATALYST | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0328342-A2 | Process for producing aromatic polyamides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-08-16 | — | — | EP | disclosed |