Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361927 | 0.89 | ALOX5AP (0.39) | ALOX5APFEN1F2RL3GPR119KDM4E | |
| SCHEMBL14941693 | 0.89 | ALOX5AP (0.39) | ALOX5APFEN1F2RL3GPR119KDM4E | |
| SCHEMBL6583997 | 0.85 | PRMT5 (0.38) | ALOX5APFEN1F2RL3GPR119MAPT | |
| SCHEMBL21985057 | 0.84 | CHRNB2 (0.53) | ALOX5APFEN1F2RL3GPR119GRM5 | |
| SCHEMBL14941701 | 0.84 | CHRNB2 (0.53) | ALOX5APFEN1F2RL3GPR119GRM5 | |
| SCHEMBL21845298 | 0.83 | ALOX5AP (0.49) | ALOX5APFEN1F2RL3GPR119MAPT | |
| SCHEMBL14941875 | 0.83 | ALOX5AP (0.45) | ALOX5APFEN1F2RL3GPR119LMNA | |
| SCHEMBL14941885 | 0.83 | ALOX5AP (0.45) | ALOX5APFEN1F2RL3GPR119LMNA | |
| SCHEMBL7475109 | 0.82 | CHRNB2 (0.54) | ALOX5APFEN1 | |
| SCHEMBL7453857 | 0.82 | CHRNB2 (0.54) | F2RL3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776030-B1 | 2,5-DISUBSTITUTED-PYRIDYL NICOTINIC LIGANDS, AND METHODS OF USE THEREOF | UNIV GEORGETOWN (US) | 2020-05-13 | — | — | EP | disclosed |