SCHEMBL21985476

SCHEMBL21985476

CC(=O)NCCCN1CC1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.59
TP53 P04637 1/20 0.59
DRD2 P14416 1/20 0.56
DRD4 P21917 1/20 0.56
MAPK1 P28482 2/20 0.56
KDM4E B2RXH2 2/20 0.56
HIF1A Q16665 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
USP2 O75604 1/20 0.51
LMNA P02545 4/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
GAA P10253 2/20 0.50
HTT P42858 1/20 0.50
PAOX Q6QHF9 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861408 1.00 SMN1; SMN2 (0.59) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL8151767 0.94 PAOX (0.55) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL18211581 0.92 SMN1; SMN2 (0.53) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL5956993 0.92 USP2 (0.58) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL3251521 0.92 MAPK1 (0.52) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL18851456 0.91 SMN1; SMN2 (0.51) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL13453975 0.90 SMN1; SMN2 (0.52) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL8761519 0.90 SMN1; SMN2 (0.52) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL23407902 0.88 SMN1; SMN2 (0.57) SMN1; SMN2TP53DRD2DRD4MAPK1
SCHEMBL18850970 0.88 SIGMAR1 (0.51) SMN1; SMN2TP53DRD2DRD4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3352290-B1 AZIRIDINO-FUNCTIONAL POLYETHER THERMALLY-CONDUCTIVE GAP FILLER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-07-17 EP disclosed
US-20220389169-A1 THERMALLY-CONDUCTIVE CURABLE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2022-12-08 US disclosed
US-20210403646-A1 ACID-CURABLE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2021-12-30 US disclosed
US-20210395455-A1 ACID-CURABLE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2021-12-23 US disclosed
US-11171370-B2 Aziridino-functional polyether thermally-conductive gap filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-11-09 US disclosed
US-20210189211-A1 THERMALLY-CONDUCTIVE GAP FILLER 3M INNOVATIVE PROPERTIES COMPANY 2021-06-24 US disclosed
US-20210189212-A1 CONTROL CURE THERMALLY-CONDUCTIVE GAP FILLER MATERIALS 3M INNOVATIVE PROPERTIES COMPANY 2021-06-24 US disclosed
EP-3819328-A1 THERMALLY-CONDUCTIVE CURABLE COMPOSITION 3M Innovative Properties Company (US) 2021-05-12 EP disclosed
EP-3650485-A1 ACID-CURABLE COMPOSITION 3M Innovative Properties Company (US) 2020-05-13 EP disclosed
EP-3650486-A1 ACID-CURABLE COMPOSITION 3M Innovative Properties Company (US) 2020-05-13 EP disclosed