Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.67 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.67 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.67 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196091 | 0.93 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11MAPK8 | |
| SCHEMBL2200115 | 0.91 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL2196948 | 0.90 | MAPK14 (0.72) | MAPK14MAPK13MAPK12MAPK11MAPK8 | |
| SCHEMBL2200606 | 0.89 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL2201704 | 0.89 | MAPK13 (0.52) | MAPK14MAPK13MAPK12MAPK11MAPK8 | |
| SCHEMBL2201708 | 0.89 | MAPK13 (0.52) | MAPK14MAPK13MAPK12MAPK11MAPK8 | |
| SCHEMBL2198645 | 0.88 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL2198471 | 0.86 | MAPK14 (0.63) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL2198867 | 0.85 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL2198908 | 0.85 | MAPK13 (0.68) | MAPK14MAPK13MAPK12MAPK11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | claimed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | MAPK14 697/4885MAPK13 1063/4885MAPK12 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.