Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17905640 | 1.00 | CA1 (0.34) | CA1CA2CA7CTSKSMN1; SMN2 | |
| SCHEMBL17904961 | 0.83 | HRH2 (0.40) | CTSKSMN1; SMN2CTSS | |
| SCHEMBL17905656 | 0.82 | KMT2A (0.42) | CA1CA2CA7CTSKSMN1; SMN2 | |
| SCHEMBL17896173 | 0.80 | PPARA (0.43) | CA1CA7CTSKMAPTCA12 | |
| SCHEMBL17905295 | 0.80 | PPARA (0.43) | CA1CA7CTSKMAPTCA12 | |
| SCHEMBL19726471 | 0.79 | CA1 (0.40) | CA1CA2CA7CTSKMAPT | |
| SCHEMBL17901141 | 0.79 | CA1 (0.40) | CA1CA2CA7CTSKMAPT | |
| SCHEMBL17901039 | 0.79 | CA1 (0.40) | CA1CA2CA7CTSKMAPT | |
| SCHEMBL17906534 | 0.77 | MAPT (0.42) | CTSKMAPTGLAKDM4EGAA | |
| SCHEMBL17905591 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |