⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17904959 | 0.79 | TSHR (0.38) | — | |
| SCHEMBL17905490 | 0.78 | SLC1A3 (0.37) | — | |
| SCHEMBL21986117 | 0.76 | CA1 (0.34) | — | |
| SCHEMBL17904801 | 0.75 | SLC1A3 (0.42) | — | |
| SCHEMBL19758142 | 0.75 | SLC1A3 (0.42) | — | |
| SCHEMBL17896267 | 0.75 | SLC1A3 (0.42) | — | |
| SCHEMBL20682884 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL17900983 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL17904838 | 0.71 | CYP2C19 (0.37) | — | |
| SCHEMBL17905492 | 0.67 | OGG1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| WO-2016109289-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109288-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |