Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918527 | 0.84 | CNR1 (0.43) | CNR1CNR2ALDH1A1CYP2D6KMT2A | |
| SCHEMBL13804337 | 0.82 | — | — | |
| SCHEMBL8443686 | 0.82 | CNR1 (0.42) | CNR1CNR2ALDH1A1CYP2D6KMT2A | |
| SCHEMBL12136871 | 0.81 | CNR1 (0.41) | CNR1CNR2ALDH1A1CYP2D6 | |
| SCHEMBL8259098 | 0.79 | CNR1 (0.40) | CNR1CNR2ALDH1A1CYP2D6KMT2A | |
| SCHEMBL24946123 | 0.77 | KDM4E (0.38) | CNR1CNR2ALDH1A1CYP2D6KMT2A | |
| SCHEMBL971440 | 0.74 | KDM4E (0.63) | CNR1CNR2KMT2AKDM4E | |
| SCHEMBL8913688 | 0.74 | CNR1 (0.38) | CNR1CNR2KMT2AKDM4E | |
| SCHEMBL971337 | 0.71 | CYP2D6 (0.70) | ALDH1A1CYP2D6KMT2AKDM4E | |
| SCHEMBL8436838 | 0.70 | SMN1; SMN2 (0.36) | CNR1ALDH1A1CYP2D6KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172214-B1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-05-13 | — | — | EP | disclosed |