Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804337 | 0.86 | — | — | |
| SCHEMBL24946123 | 0.80 | KDM4E (0.38) | CNR1KDM4EKMT2ACNR2 | |
| SCHEMBL7870008 | 0.78 | KDM4E (0.59) | KDM4EKMT2A | |
| SCHEMBL971440 | 0.77 | KDM4E (0.63) | CNR1KDM4EKMT2ACNR2 | |
| SCHEMBL12918527 | 0.76 | CNR1 (0.43) | CNR1KDM4EKMT2ACNR2 | |
| SCHEMBL8443686 | 0.74 | CNR1 (0.42) | CNR1KDM4EKMT2ACNR2 | |
| SCHEMBL21986166 | 0.74 | CNR1 (0.42) | CNR1KDM4EKMT2ACNR2 | |
| SCHEMBL7876466 | 0.73 | ALDH1A1 (0.46) | KDM4EKMT2A | |
| SCHEMBL12136871 | 0.73 | CNR1 (0.41) | CNR1CNR2 | |
| SCHEMBL3554211 | 0.72 | KMT2A (0.42) | CNR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |