SCHEMBL21986567

SCHEMBL21986567

CC(C)(C)Oc1c(F)c(F)c(N)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4344192 0.87
SCHEMBL12680314 0.84 CA1 (0.31)
SCHEMBL6432829 0.78 CA1 (0.31)
SCHEMBL7868528 0.77
SCHEMBL31181834 0.77
SCHEMBL13641832 0.77 TAS1R3 (0.31)
SCHEMBL7871425 0.77
SCHEMBL24221432 0.75
SCHEMBL7641451 0.75
SCHEMBL7868536 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345441-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-11-13 US disclosed
US-20250276067-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-09-04 US disclosed
US-20220088204-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2022-03-24 US disclosed
EP-3914241-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME Yale University (US) 2021-12-01 EP disclosed
US-20210085796-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME YALE UNIVERSITY 2021-03-25 US disclosed
US-20210085796-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME YALE UNIVERSITY 2021-03-25 US disclosed
WO-2020154672-A1 ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME YALE UNIVERSITY (US) 2020-07-30 WO disclosed
EP-3659307-A1 Anticancer Drugs and Methods of Making and Using Same Yale University (US) 2020-06-03 EP disclosed