Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922542 | 0.86 | IDH1 (0.56) | IDH1CYP1A2HNF4ABCL2BCL2L1 | |
| SCHEMBL24928859 | 0.84 | — | — | |
| SCHEMBL26003882 | 0.83 | — | — | |
| SCHEMBL27877433 | 0.81 | ALDH1A1 (0.54) | IDH1CYP1A2PRSS1PRSS2PRSS3 | |
| SCHEMBL16846166 | 0.79 | — | — | |
| SCHEMBL2056356 | 0.78 | CYP1A2 (0.53) | CYP1A2CTDSP1HSD17B10 | |
| SCHEMBL15345371 | 0.78 | CTDSP1 (0.58) | CYP1A2CTDSP1 | |
| SCHEMBL21585559 | 0.77 | AKR1B1 (0.58) | CYP1A2CTDSP1CYP2C19HSD17B10 | |
| SCHEMBL15345635 | 0.76 | PRSS1 (0.44) | IDH1CYP1A2PRSS1PRSS2PRSS3 | |
| SCHEMBL27919165 | 0.76 | TRPV1 (0.42) | IDH1PRSS1PRSS2PRSS3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659593-A1 | TRMT2A INHIBITORS FOR USE IN THE TREATMENT OF POLYGLUTAMINE DISEASES | Forschungszentrum Jülich GmbH/ Abteilung RP-PT (DE) | 2020-06-03 | — | — | EP | disclosed |