SCHEMBL21990725

SCHEMBL21990725

[CH2]CC(N)=C(C)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29037258 0.77 ALDH1A1 (0.38) ALDH1A1TDP1
SCHEMBL23005838 0.77 ALDH1A1 (0.38) ALDH1A1TDP1
SCHEMBL22092264 0.77 ALDH1A1 (0.38) ALDH1A1TDP1
SCHEMBL21251208 0.75 ALDH1A1 (0.36) ALDH1A1TDP1
SCHEMBL18953058 0.73 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL9014226 0.73
SCHEMBL18953059 0.73 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL23844633 0.68 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL790457 0.66
SCHEMBL18574041 0.65 ALDH1A1 (0.32) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562852-B1 METHODS OF MAKING POLYMERS WITH REDUCED TACK, AND RUBBER COMPOSITIONS INCORPORATING THESE POLYMERS FIRESTONE POLYMERS LLC (US) 2023-04-19 EP disclosed
US-11332556-B2 Methods of making polymers with reduced tack, and rubber compositions incorporating these polymers BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2022-05-17 US disclosed
US-20200172639-A1 Methods Of Making Polymers With Reduced Tack, And Rubber Compositions Incorporating These Polymers FIRESTONE POLYMERS, LLC (US) 2020-06-04 US disclosed
CN-108026188-A Silane-functionalized polymer and preparation and use its method 株式会社普利司通 2018-05-11 CN disclosed