Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988583 | 0.80 | PIK3CD (0.47) | PIK3CDPER2 | |
| SCHEMBL21988582 | 0.78 | PIK3CD (0.41) | PIK3CDPER2 | |
| SCHEMBL17662297 | 0.77 | GLA (0.41) | — | |
| SCHEMBL21990966 | 0.75 | PIK3CD (0.46) | PIK3CDPER2CRY2 | |
| SCHEMBL17662298 | 0.72 | GLA (0.44) | — | |
| SCHEMBL6888871 | 0.70 | SMN1; SMN2 (0.41) | PRMT5WDR77PIK3CDPER2CRY2 | |
| SCHEMBL17662300 | 0.69 | GLA (0.45) | PRMT5WDR77PER2 | |
| SCHEMBL12409668 | 0.67 | PDK2 (0.40) | PRMT5WDR77PER2CRY2 | |
| SCHEMBL4875078 | 0.67 | ALDH1A1 (0.30) | — | |
| SCHEMBL6204103 | 0.66 | USP2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201205-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |