SCHEMBL21991683

SCHEMBL21991683

CC[C@@H](C)n1nnc2cc(P)ccc21

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 8/20 0.62
HPGD P15428 3/20 0.42
HCAR2 Q8TDS4 1/20 0.42
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
DHFR P00374 1/20 0.30
SLC2A1 P11166 1/20 0.30
SLC9A1 P19634 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19848521 0.83 HCAR3 (0.63) HCAR3HPGDHCAR2CYP1A2CYP2C19
SCHEMBL19911616 0.81 HCAR3 (0.62) HCAR3HPGDHCAR2ALDH1A1GLA
SCHEMBL19911585 0.81 HCAR3 (0.62) HCAR3HPGDHCAR2CYP1A2CYP2C19
SCHEMBL19848187 0.81 HCAR3 (0.58) HCAR3HPGDHCAR2MEN1KMT2A
SCHEMBL19848416 0.79 HCAR3 (0.59) HCAR3HPGDHCAR2MEN1KMT2A
SCHEMBL19911500 0.79 HCAR3 (0.59) HCAR3HPGDHCAR2MEN1KMT2A
SCHEMBL19915946 0.78 HCAR3 (0.58) HCAR3HPGDHCAR2CYP1A2CYP2C19
SCHEMBL11402863 0.77 HCAR3 (0.56) HCAR3CYP1A2CYP2C19ALDH1A1SMN1; SMN2
SCHEMBL6044065 0.77 HCAR3 (1.00) HCAR3HPGDHCAR2
SCHEMBL19911544 0.76 HCAR3 (0.59) HCAR3HPGDHCAR2CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3467930-B1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY ASAHI CHEMICAL IND (JP) 2020-05-13 EP disclosed