Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179962 | 0.85 | SLC7A5 (0.36) | NR3C1PGRNR3C2MAOBNOS3 | |
| SCHEMBL19999803 | 0.80 | HPGD (0.36) | HPGDMAOB | |
| SCHEMBL21993361 | 0.80 | HPGD (0.36) | HPGDMAOBKMT2AMEN1LMNA | |
| SCHEMBL21992337 | 0.80 | MAOB (0.39) | HPGDMAOBBACE1KMT2AMEN1 | |
| SCHEMBL19962120 | 0.80 | HPGD (0.38) | HPGDMAOBKMT2AMEN1SLC6A3 | |
| SCHEMBL21993366 | 0.78 | MAOB (0.40) | HPGDMAOBKMT2AMEN1LMNA | |
| SCHEMBL19999802 | 0.78 | S1PR1 (0.41) | HPGDMAOBKMT2AMEN1 | |
| SCHEMBL21992634 | 0.78 | SMN1; SMN2 (0.39) | HPGDMAOBSLC6A3 | |
| SCHEMBL21992128 | 0.77 | MAOB (0.37) | HPGDMAOBKMT2ALMNA | |
| SCHEMBL19999809 | 0.77 | MAOB (0.38) | HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286166-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2020-05-13 | — | — | EP | disclosed |