SCHEMBL219922

SCHEMBL219922

Cc1cc(Cl)cc(C(=O)O)c1N

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.66
CYP3A4 P08684 1/20 0.55
AKR1C4 P17516 1/20 0.47
AKR1C3 P42330 1/20 0.47
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47
ALDH1A1 P00352 2/20 0.44
TP53 P04637 1/20 0.44
NOTUM Q6P988 1/20 0.43
MYC P01106 3/20 0.43
HSD17B10 Q99714 2/20 0.43
HPGD P15428 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29917566 1.00 KDM4E (0.66) KDM4ECYP3A4AKR1C4AKR1C3AKR1C2
Hydrochloric Acid SCHEMBL29208275 0.98 KDM4E (0.63) KDM4ECYP3A4AKR1C4AKR1C3AKR1C2
SCHEMBL28704965 0.85 CYP3A4 (0.65) KDM4ECYP3A4AKR1C4AKR1C3AKR1C2
SCHEMBL14234313 0.84 KDM4E (0.46) KDM4ECYP3A4AKR1C4AKR1C3AKR1C2
SCHEMBL29373932 0.84 KDM4E (0.46) KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2
SCHEMBL19646057 0.84 KDM4E (0.46) KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2
SCHEMBL26603550 0.84 KDM4E (0.46) KDM4ECYP3A4ALDH1A1HPGDKMT2A
SCHEMBL27868371 0.80 CYP3A4 (0.55) KDM4ECYP3A4AKR1C4AKR1C3AKR1C2
SCHEMBL25262460 0.79 KDM4E (0.42) KDM4ECYP3A4AKR1C4AKR1C3AKR1C2
SCHEMBL384330 0.79 KDM4E (0.42) KDM4ECYP3A4ALDH1A1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730859-B Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 青岛科技大学 2025-06-13 CN claimed
EP-3902792-B1 PROCESS FOR PREPARATION OF ANTHRANILAMIDES UPL LTD (IN) 2025-05-21 EP claimed
CN-119500077-A Preparation method and application of efficient desulfurizing agent 江苏德隆环保工程有限公司 2025-02-25 CN claimed
CN-119431170-A Method for producing 2-amino-5-chloro-3-methylbenzoic acid by reaction crystallization 宁波诺丁汉大学 2025-02-14 CN claimed
CN-119143618-A Preparation method of 2-amino-3-methyl-5-chlorobenzoic acid 湖北泰盛化工有限公司 2024-12-17 CN claimed
CN-115611763-B O-aminobenzoyl Process for producing amine derivative 山东友道化学有限公司 2024-12-13 CN claimed
CN-119059923-A Scandium catalytic synthesis process of 2-amino-5-chloro-3-methylbenzoic acid 南京工业大学 2024-12-03 CN claimed
CN-118771987-A Preparation method of 2-nitro-3-methyl-5-chlorobenzoic acid 帕潘纳(北京)科技有限公司 2024-10-15 CN claimed
CN-115745959-B Industrial production method of chlorantraniliprole 山东友道化学有限公司 2024-06-21 CN claimed
CN-115772090-B Synthesis method of chlorantraniliprole key intermediate 九江善水科技股份有限公司 2024-06-07 CN claimed
CN-111517975-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 江苏七洲绿色化工股份有限公司 2020-08-11 CN claimed
CN-110615780-A Preparation method of chlorantraniliprole 南通雅本化学有限公司 2019-12-27 CN claimed
CN-104031026-A O-formylamino benzamide derivatives containing N-cyano sulfone(sulfur)imine, preparation method thereof and uses thereof UNIV NANKAI 2014-09-10 CN claimed
EP-1903030-B1 Method for catalytic manufacture of aromatic or heteroaromatic nitriles SALTIGO GMBH (DE) 2014-06-04 EP claimed
CN-103058993-B Chlorantraniliprole preparation method UNIV HENAN NORMAL 2014-06-04 CN claimed
CN-103172613-A O-formamido benzamide derivative containing N-cyano sulfone (sulfur) imine and preparation method and application thereof UNIV NANKAI 2013-06-26 CN claimed
CN-103058993-A Chlorantraniliprole preparation method UNIV HENAN NORMAL 2013-04-24 CN claimed
US-7592452-B2 Process for catalytically preparing aromatic or heteroaromatic nitriles SALTIGOGMBH (DE) 2009-09-22 US claimed
US-20090062541-A1 Process for catalytically preparing aromatic or heteroaromatic nitriles SALTIGO GMBH (DE) 2009-03-05 US claimed
EP-1903030-A1 Method for catalytic manufacture of aromatic or heteroaromatic nitriles Saltigo GmbH (DE) 2008-03-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062541-A1 Process for catalytically preparing aromatic or heteroaromatic nitriles AHR, PAH, AOC3 KDM4E 612/4885CYP3A4 12/4885AKR1C4 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.