SCHEMBL384330

SCHEMBL384330

CNC(=O)c1cc(Cl)cc(C)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
SCN10A Q9Y5Y9 3/20 0.40
SCN9A Q15858 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
SCN1A P35498 1/20 0.40
KCNH2 Q12809 1/20 0.40
SCN5A Q14524 1/20 0.40
JAK2 O60674 1/20 0.39
CYP3A4 P08684 1/20 0.38
ALDH1A1 P00352 2/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
IKBKB O14920 1/20 0.37
BCL2L1 Q07817 1/20 0.37
WDR5 P61964 2/20 0.36
BRAF P15056 1/20 0.36
HDAC1 Q13547 1/20 0.36
FADS1 O60427 1/20 0.36
EZH2 Q15910 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30808427 0.98 KDM4E (0.41) KDM4ESCN10ASCN9ASCN2ASCN3A
Phosphoric Acid SCHEMBL31400022 0.95 KDM4E (0.39) KDM4ESCN10ASCN9ASCN2ASCN3A
Sulfuric Acid SCHEMBL31400033 0.94 IKBKB (0.40) KDM4ESCN10ASCN9ASCN2ASCN3A
SCHEMBL27930599 0.86 ALDH1A1 (0.51) KDM4ECYP3A4ALDH1A1GLAGAA
SCHEMBL2061521 0.84 ALDH1A1 (0.49) KDM4ESCN10ASCN9ASCN2ASCN3A
SCHEMBL14697698 0.83 PTGS2 (0.41) KDM4ECYP3A4ALDH1A1GLAGAA
SCHEMBL24458108 0.81 SCN9A (0.39) SCN10ASCN9ASCN2ASCN3ASCN1A
SCHEMBL24458105 0.81 EZH2 (0.43) KDM4ESCN10ASCN9ASCN2ASCN3A
SCHEMBL2131841 0.81 POLB (0.47) KDM4EALDH1A1BCL2L1
SCHEMBL2489605 0.81 ALOX5 (0.46) KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676908-A1 PHOTOCHEMICAL SYSTEMS AND METHODS FOR PREPARING CYANOBENZAMIDES FMC Corporation (US) 2026-01-14 EP claimed
CN-116730859-B Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 青岛科技大学 2025-06-13 CN claimed
CN-120058546-A 2-Amino-5-chloro-N, 3-dimethylbenzamide production process 九江善水科技股份有限公司 2025-05-30 CN claimed
CN-119977940-A Chlorantraniliprole Process for the preparation of amine impurities 合肥工业大学 2025-05-13 CN claimed
CN-119824494-A Cyanide-free silver-plated palladium alloy stabilizer, preparation device, preparation method and application 重庆立道新材料科技有限公司 2025-04-15 CN claimed
CN-119707730-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 重庆华歌生物化学有限公司 2025-03-28 CN claimed
CN-119330851-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 江西天戌药业有限公司 2025-01-21 CN claimed
US-20250002447-A1 METHOD FOR PREPARING 2-AMINO-5-CHLORO-N,3-DIMETHYLBENZAMIDE HUBEI KECY CHEMICAL CO., LTD. (CN) 2025-01-02 US claimed
CN-116535388-B Chlorantraniliprole Process for the preparation of amides 江苏七洲绿色科技研究院有限公司 2024-12-10 CN claimed
CN-115057844-B Chlorantraniliprole Process for the preparation of amides 江苏七洲绿色科技研究院有限公司 2024-12-06 CN claimed
CN-115583895-A Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide 苏州开元民生科技股份有限公司 2023-01-10 CN claimed
CN-111517975-B Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 江苏七洲绿色化工股份有限公司 2022-12-16 CN claimed
CN-115417781-A Method for preparing chlorantraniliprole intermediate K amine 西安凯立新材料股份有限公司 2022-12-02 CN claimed
CN-115197085-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 九江善水科技股份有限公司 2022-10-18 CN claimed
CN-110845341-B Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 苏州开元民生科技股份有限公司 2022-10-14 CN claimed
EP-4061132-A1 PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE Gharda Chemicals Limited (IN) 2022-09-28 EP claimed
CN-115057844-A Preparation method of chlorantraniliprole 江苏七洲绿色科技研究院有限公司 2022-09-16 CN claimed
CN-113480518-A Method for synthesizing chlorantraniliprole 江西汇和化工有限公司 2021-10-08 CN claimed
WO-2021099978-A1 PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE GHARDA CHEMICALS LIMITED (IN) 2021-05-27 WO claimed
WO-2021033172-A1 PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE EUROFINS ADVINUS LIMITED (IN) 2021-02-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002447-A1 METHOD FOR PREPARING 2-AMINO-5-CHLORO-N,3-DIMETHYLBENZAMIDE HNMT, CA3, NAAA KDM4E 389/4885SCN10A 2449/4885SCN9A 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.