Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885080 | 0.83 | F10 (0.53) | F10CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL222420 | 0.80 | F10 (0.78) | F10ALDH1A1HPGDL3MBTL1NPSR1 | |
| SCHEMBL4592742 | 0.78 | F10 (0.70) | F10ALDH1A1 | |
| SCHEMBL220028 | 0.78 | F10 (0.70) | F10ALDH1A1 | |
| SCHEMBL219921 | 0.76 | F10 (0.80) | F10ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL219798 | 0.76 | F10 (1.00) | F10 | |
| SCHEMBL219802 | 0.75 | F10 (0.65) | F10 | |
| SCHEMBL4592816 | 0.75 | F10 (0.65) | F10L3MBTL1NPC1RAB9A | |
| SCHEMBL221054 | 0.75 | F10 (0.65) | F10L3MBTL1NPC1RAB9A | |
| SCHEMBL3879613 | 0.74 | F10 (0.59) | F10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088925-B2 | low molecular weight factor Xa specific blood clotting inhibitors; less side effects; 5-Chloro-thiophene-2-carboxylic acid [2-(1-isopropyl-piperidin-4-ylsulfamoyl)-ethyl]-amide; thromboembolic diseases or restenosis; antithrombotic agents | SANOFI-AVENTIS (FR) | 2012-01-03 | — | — | US | disclosed |