Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221054 | 1.00 | F10 (0.65) | F10CHRM1CHRM5L3MBTL1KDM5A | |
| SCHEMBL4592742 | 0.88 | F10 (0.70) | F10 | |
| SCHEMBL220028 | 0.88 | F10 (0.70) | F10 | |
| SCHEMBL219802 | 0.80 | F10 (0.65) | F10 | |
| SCHEMBL219798 | 0.79 | F10 (1.00) | F10 | |
| SCHEMBL219921 | 0.76 | F10 (0.80) | F10L3MBTL1NPC1RAB9A | |
| SCHEMBL222420 | 0.75 | F10 (0.78) | F10L3MBTL1NPC1RAB9A | |
| SCHEMBL219936 | 0.75 | F10 (0.61) | F10L3MBTL1NPC1RAB9A | |
| Fumaric Acid SCHEMBL221972 | 0.74 | F10 (0.89) | F10 | |
| SCHEMBL220661 | 0.73 | F10 (0.89) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |