Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042555 | 0.83 | NOTUM (0.49) | PTPN1SMN1; SMN2NOTUMNPC1RAB9A | |
| SCHEMBL29616577 | 0.83 | NOTUM (0.49) | PTPN1SMN1; SMN2NOTUMNPC1RAB9A | |
| SCHEMBL21995470 | 0.78 | TDP1 (0.39) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4062935 | 0.78 | NPC1 (0.40) | PTPN1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL4544654 | 0.76 | ALDH1A1 (0.39) | PTPN1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL21995414 | 0.75 | CYP3A4 (0.39) | SMN1; SMN2NOTUMRAB9AMAPTMAPK1 | |
| SCHEMBL9809603 | 0.74 | PTPN1 (0.37) | PTPN1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL30882458 | 0.73 | PTPN1 (0.41) | PTPN1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL30623436 | 0.72 | PTPN1 (0.39) | PTPN1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL14958302 | 0.72 | PTPN1 (0.39) | PTPN1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |