Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.81 |
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | PPARD | Q03181 | 7/20 | 0.81 |
| ▸ | PPARA | Q07869 | 7/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | FABP4 | P15090 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | TLR2 | O60603 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.81 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 1/20 | 0.81 |
| ▸ | PDE4A | P27815 | 1/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL28091700 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL11071743 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL9421271 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL28323905 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL1356041 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL11091462 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL8621559 | 0.98 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28280402 | 0.98 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7528139 | 0.98 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL12817527 | 0.98 | AKR1B1 (0.80) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117510-B | Grease composition, clutch and electric window motor | NOK克鲁勃株式会社 | 2022-03-25 | — | — | CN | disclosed |
| CN-107406792-B | Grease composition | NOK克鲁伯有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-106573304-B | Silver powder and method for producing same | 同和电子科技有限公司 | 2020-03-03 | — | — | CN | disclosed |
| CN-110027208-A | A kind of phase change composite material and its preparation method and application | 宁波石墨烯创新中心有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109777368-A | A kind of porous carbon composite phase-change material and preparation method thereof | 宁波石墨烯创新中心有限公司 | 2019-05-21 | — | — | CN | disclosed |
| US-10170213-B2 | Silver powder and method for producing same | DOWA ELECTRONICS MATERIALS CO., LTD. (JP) | 2019-01-01 | — | — | US | disclosed |
| US-20180158564-A1 | SILVER POWDER AND METHOD FOR PRODUCING SAME | DOWA ELECTRONICS MATERIALS CO., LTD. (JP) | 2018-06-07 | — | — | US | disclosed |
| US-9984788-B2 | Silver powder and method for producing same | DOWA ELECTRONICS MATERIALS CO., LTD. (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20170206998-A1 | SILVER POWDER AND METHOD FOR PRODUCING SAME | DOWA ELECTRONICS MATERIALS CO., LTD. (JP) | 2017-07-20 | — | — | US | disclosed |
| US-7979016-B2 | Image forming apparatus and protective agent block | RICOH COMPANY, LTD. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20090290920-A1 | IMAGE FORMING APPARATUS AND PROTECTIVE AGENT BLOCK | RICOH COMPANY, LTD. (JP) | 2009-11-26 | — | — | US | disclosed |
| CN-1241905-A | Compositions and methods for treating plants with exogenous chemicals | MONSANTO CO (US) | 2000-01-19 | — | — | CN | disclosed |