Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.51 |
| ▸ | SYK | P43405 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200571 | 0.88 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL2201685 | 0.86 | MAPK14 (0.52) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL2199484 | 0.83 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2196274 | 0.81 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL2199752 | 0.79 | MAPK14 (0.61) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2201715 | 0.79 | MAPK14 (0.51) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5988678 | 0.76 | MAPK13 (0.79) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL1907242 | 0.74 | MAPK14 (0.81) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL2198903 | 0.74 | MAPK14 (0.71) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL1906099 | 0.72 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | claimed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | MAPK13 1063/4885MAPK12 955/4885MAPK11 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.