Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347628 | 1.00 | MAPK1 (0.43) | MAPK1LMNANPSR1KDM4EPDE7A | |
| SCHEMBL22057630 | 0.81 | MAPK1 (0.46) | MAPK1LMNANPSR1KDM4EPDE7A | |
| SCHEMBL22056905 | 0.80 | MAPK1 (0.43) | MAPK1LMNANPSR1KDM4EPDE7A | |
| SCHEMBL22056903 | 0.78 | KMT2A (0.43) | MAPK1LMNANPSR1KDM4EALDH1A1 | |
| SCHEMBL22056901 | 0.75 | MAPK1 (0.43) | MAPK1LMNAKDM4EPDE7AALDH1A1 | |
| SCHEMBL21995257 | 0.74 | MAPK1 (0.45) | MAPK1LMNAKDM4EPDE7ANPC1 | |
| SCHEMBL1064871 | 0.72 | KDM4E (0.45) | MAPK1LMNANPSR1KDM4ENPC1 | |
| SCHEMBL3285141 | 0.71 | KDM4E (0.47) | MAPK1NPSR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL15206821 | 0.68 | KMT2A (0.43) | MAPK1LMNAKDM4EPDE7AALDH1A1 | |
| SCHEMBL24182595 | 0.68 | ALDH1A1 (0.56) | MAPK1LMNANPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220013730-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK KGAA (DE) | 2022-01-13 | — | — | US | disclosed |
| EP-3887478-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109434-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020109434-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220013730-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2C19, ESR1 | MAPK1 565/4885LMNA 3208/4885NPSR1 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.