Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817525 | 0.82 | TDP1 (0.39) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL8756974 | 0.81 | TDP1 (0.48) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL9685032 | 0.81 | TDP1 (0.48) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL1003317 | 0.79 | TRPA1 (0.45) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL30271542 | 0.79 | TRPA1 (0.50) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL19205698 | 0.79 | TRPA1 (0.50) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL5669794 | 0.79 | TRPA1 (0.50) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL11918179 | 0.77 | TDP1 (0.44) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL21331650 | 0.76 | TRPA1 (0.47) | TDP1TP53TRPA1LMNACHRM1 | |
| SCHEMBL21331658 | 0.76 | TRPA1 (0.47) | TDP1TP53TRPA1LMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |