⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452721 | 1.00 | — | — | |
| SCHEMBL453892 | 0.81 | — | — | |
| SCHEMBL12005 | 0.81 | — | — | |
| SCHEMBL450255 | 0.70 | — | — | |
| SCHEMBL28274294 | 0.69 | DYRK1A (0.56) | — | |
| SCHEMBL16720927 | 0.68 | DYRK1A (0.43) | — | |
| Benzothiophene SCHEMBL27791811 | 0.67 | CA12 (0.41) | — | |
| Benzothiophene SCHEMBL20473352 | 0.67 | CA12 (0.41) | — | |
| Benzothiophene SCHEMBL28337252 | 0.67 | CTNNB1 (0.37) | — | |
| SCHEMBL452819 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4840 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999727-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-06-04 | — | — | US | claimed |
| CN-113272292-B | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2024-04-12 | — | — | CN | claimed |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | claimed |
| US-20230242568-A1 | POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | MIRECA MEDICINES GMBH (DE) | 2023-08-03 | — | — | US | claimed |
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | claimed |
| US-20230159522-A1 | BCL-2 INHIBITOR | BEONE MEDICINES I GMBH (CH) | 2023-05-25 | — | — | US | claimed |
| US-20230113778-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-04-13 | — | — | US | claimed |
| EP-4149452-A1 | COMBINATION TREATMENT OF LIVER DISORDERS | Terns Pharmaceuticals, Inc. (US) | 2023-03-22 | — | — | EP | claimed |
| EP-4149453-A1 | COMBINATION TREATMENT OF LIVER DISORDERS | Terns Pharmaceuticals, Inc. (US) | 2023-03-22 | — | — | EP | claimed |
| CN-115811973-A | Combination therapy for liver disorders | 拓臻制药公司 | 2023-03-17 | — | — | CN | claimed |
| EP-0565965-A2 | Benzo b thiophen-5-yl derivative and process for producing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | claimed |
| EP-0171037-B1 | 3-CARBONYL-1-AMINOALKYL-1H-INDOLES USEFUL AS ANALGESICS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1992-06-17 | — | — | EP | claimed |
| US-5041559-A | Having epoxy and silyl groups | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-20 | — | — | US | claimed |
| US-5037855-A | Silane group containing, chemical intermediates | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-06 | — | — | US | claimed |
| US-4902812-A | Optically active alcohols, process for producing the same, and process for resolving the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-20 | — | — | US | claimed |
| US-RE32761-E | ANALGESICS, ANTIRHEUMATIC AND ANTIINFLAMMATORY AGENT | STERLING DRUG INC. (US) | 1988-10-04 | — | — | US | claimed |
| US-4581354-A | ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1986-04-08 | — | — | US | claimed |
| EP-0171037-A2 | 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof | STERLING WINTHROP INC. (US) | 1986-02-12 | — | — | EP | claimed |
| EP-0139917-A1 | Pharmaceutical preparations, acylated hydrazine derivatives, methods for their preparation | CIBA-GEIGY AG (CH) | 1985-05-08 | — | — | EP | claimed |