Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 13/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996198 | 1.00 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20NAA50 | |
| SCHEMBL21996248 | 0.89 | PTGS1 (0.54) | PTGS1KCNH2VNN1ZDHHC20MEN1 | |
| SCHEMBL21996249 | 0.89 | PTGS1 (0.54) | PTGS1KCNH2VNN1ZDHHC20MEN1 | |
| SCHEMBL19832435 | 0.88 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20NAA50 | |
| SCHEMBL16685028 | 0.88 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20NAA50 | |
| SCHEMBL7761533 | 0.88 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20MEN1 | |
| SCHEMBL7760567 | 0.88 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20MEN1 | |
| SCHEMBL21996513 | 0.87 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL21996263 | 0.86 | PTGS1 (0.51) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL22057169 | 0.86 | PTGS1 (0.51) | PTGS1KCNH2VNN1ZDHHC20MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230107216-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) | 2023-04-06 | — | — | US | disclosed |
| EP-3887353-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | Comet Therapeutics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020113209-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | COMET THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230107216-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | VNN1, NQO1, VKORC1 | PTGS1 1468/4885KCNH2 3526/4885VNN1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.