SCHEMBL21996465

SCHEMBL21996465

CC(C)[Si](C#Cc1ccc2cc3ccccc3cc2c1C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP1A1 P04798 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CACNA2D1 P54289 1/20 0.31
CACNB2 Q08289 1/20 0.31
CACNA1C Q13936 1/20 0.31
MAPT P10636 1/20 0.30
UGT2B7 P16662 1/20 0.30
ERBB2 P04626 1/20 0.30
FYN P06241 1/20 0.30
MAOA P21397 1/20 0.30
ACHE P22303 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1657492 0.99 CYP1B1 (0.33) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A
SCHEMBL17442987 0.99 CYP1B1 (0.33) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A
Thiophene SCHEMBL5371093 0.91
SCHEMBL26661844 0.86 HPRT1 (0.36) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A
SCHEMBL27725041 0.86 CACNA2D1 (0.35) CYP1B1CYP1A2CYP1A1HSD17B10CACNA2D1
SCHEMBL9473040 0.83 ALDH1A1 (0.34) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A
SCHEMBL27814779 0.83 ALDH1A1 (0.33) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A
SCHEMBL20044956 0.83 CACNA2D1 (0.35) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A
SCHEMBL1270205 0.83 CACNA2D1 (0.35) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A
SCHEMBL29360481 0.82 CACNA2D1 (0.37) CYP1B1CYP1A2CYP1A1ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3887480-A1 PHOTON UPCONVERSION NANOCAPSULES FOR 3D PRINTING AND OTHER APPLICATIONS President and Fellows of Harvard College (US) 2021-10-06 EP disclosed
WO-2020113018-A1 PHOTON UPCONVERSION NANOCAPSULES FOR 3D PRINTING AND OTHER APPLICATIONS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-06-04 WO disclosed