Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 4/20 | 0.57 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17674479 | 0.93 | KLK7 (0.63) | KLK7STSMEN1KMT2AHCRTR2 | |
| SCHEMBL13495419 | 0.91 | KLK7 (0.54) | KLK7STSMEN1KMT2AHCRTR2 | |
| SCHEMBL12239673 | 0.89 | KLK7 (0.59) | KLK7STSMEN1KMT2AHCRTR2 | |
| SCHEMBL2983392 | 0.88 | KLK7 (0.53) | KLK7STSMEN1KMT2AHCRTR2 | |
| SCHEMBL2984486 | 0.87 | KLK7 (0.56) | KLK7STSMEN1KMT2AGPR119 | |
| SCHEMBL7698816 | 0.86 | KLK7 (0.55) | KLK7STSMEN1KMT2AGPR119 | |
| SCHEMBL7511892 | 0.86 | KLK7 (0.55) | KLK7STSMEN1KMT2AGPR119 | |
| SCHEMBL1150828 | 0.86 | KLK7 (0.55) | KLK7STSMEN1KMT2AGPR119 | |
| SCHEMBL16732580 | 0.86 | KLK7 (0.55) | KLK7STSMEN1KMT2AGPR119 | |
| SCHEMBL23424922 | 0.85 | KLK7 (0.54) | KLK7MEN1KMT2AHCRTR2KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113077-A9 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020113077-A1 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-06-04 | — | — | WO | disclosed |