Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17781107 | 1.00 | SMPD3 (0.45) | SMPD3IRAK4 | |
| SCHEMBL21997749 | 1.00 | SMPD3 (0.45) | SMPD3IRAK4 | |
| SCHEMBL21996954 | 1.00 | SMPD3 (0.45) | SMPD3IRAK4 | |
| SCHEMBL26765532 | 0.91 | SMPD3 (0.44) | SMPD3IRAK4 | |
| SCHEMBL26765529 | 0.91 | SMPD3 (0.44) | SMPD3IRAK4 | |
| SCHEMBL21996924 | 0.87 | SMPD3 (0.50) | SMPD3IRAK4 | |
| SCHEMBL25338767 | 0.86 | SMPD3 (0.46) | SMPD3IRAK4 | |
| SCHEMBL25337143 | 0.86 | SMPD3 (0.46) | SMPD3IRAK4 | |
| SCHEMBL25338829 | 0.86 | SMPD3 (0.46) | SMPD3IRAK4 | |
| SCHEMBL23744414 | 0.85 | ALDH1A1 (0.52) | SMPD3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886904-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020113233-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |