SCHEMBL21998597

SCHEMBL21998597

CCC1C=CCc2cccc(C)c21

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.38
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAP3K14 Q99558 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12506887 0.75 MAP3K14 (0.39) ATMSLC6A2SLC6A3ALDH1A1MAP3K14
SCHEMBL14712111 0.75 ATM (0.37) ATMSLC6A2SLC6A3ALDH1A1MAP3K14
SCHEMBL11503546 0.73 HTR2A (0.35) HTR2AHTR2C
SCHEMBL18673963 0.63 ATM (0.34) ATM
SCHEMBL527813 0.63 ACHE (0.41) SLC6A2SLC6A3HTR2AHTR2CHTR2B
SCHEMBL7608278 0.63 HTR2A (0.34) HTR2A
SCHEMBL13849180 0.62 HTR2C (0.32) HTR2AHTR2CHTR2BALDH1A1
SCHEMBL25506825 0.62 MAP3K14 (0.47) SLC6A2SLC6A3HTR2AHTR2CHTR2B
SCHEMBL11788924 0.61 CYP1A2 (0.36) ALDH1A1
SCHEMBL19828136 0.60 SLC6A2 (0.38) SLC6A2SLC6A3HTR2CMAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200148856-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND MOLDED PRODUCT MITSUI CHEMICALS, INC. (JP) 2020-05-14 US disclosed